Usefulness of measuring both body mass index and waist circumference for the estimation of visceral adiposity and related cardiometabolic risk profile (from the INSPIRE ME IAA study).
Identifieur interne : 002664 ( Main/Exploration ); précédent : 002663; suivant : 002665Usefulness of measuring both body mass index and waist circumference for the estimation of visceral adiposity and related cardiometabolic risk profile (from the INSPIRE ME IAA study).
Auteurs : Julie-Anne Nazare [France] ; Jessica Smith [États-Unis] ; Anne-Laure Borel [France] ; Pablo Aschner [Colombie] ; Phil Barter [Australie] ; Luc Van Gaal [Belgique] ; Chee Eng Tan [Singapour] ; Hans-Ulrich Wittchen [Allemagne] ; Yuji Matsuzawa [Japon] ; Takashi Kadowaki [Japon] ; Robert Ross [Canada] ; Claire Brulle-Wohlhueter [France] ; Natalie Alméras [Canada] ; Steven M. Haffner [États-Unis] ; Beverley Balkau [France] ; Jean-Pierre Després [Canada]Source :
- The American journal of cardiology [ 1879-1913 ] ; 2015.
Descripteurs français
- KwdFr :
- Adulte d'âge moyen, Femelle, Foie (imagerie diagnostique), Graisse intra-abdominale (imagerie diagnostique), Humains, Indice de masse corporelle, Mâle, Obésité (diagnostic), Obésité (imagerie diagnostique), Obésité abdominale (diagnostic), Obésité abdominale (imagerie diagnostique), Sujet âgé, Surpoids (diagnostic), Surpoids (imagerie diagnostique), Syndrome métabolique X (diagnostic), Tomodensitométrie, Tour de taille, Évaluation des risques ().
- MESH :
- diagnostic : Obésité, Obésité abdominale, Surpoids, Syndrome métabolique X.
- imagerie diagnostique : Foie, Graisse intra-abdominale, Obésité, Obésité abdominale, Surpoids.
- Adulte d'âge moyen, Femelle, Humains, Indice de masse corporelle, Mâle, Sujet âgé, Tomodensitométrie, Tour de taille, Évaluation des risques.
English descriptors
- KwdEn :
- Aged, Body Mass Index, Female, Humans, Intra-Abdominal Fat (diagnostic imaging), Liver (diagnostic imaging), Male, Metabolic Syndrome X (diagnosis), Middle Aged, Obesity (diagnosis), Obesity (diagnostic imaging), Obesity, Abdominal (diagnosis), Obesity, Abdominal (diagnostic imaging), Overweight (diagnosis), Overweight (diagnostic imaging), Risk Assessment (methods), Tomography, X-Ray Computed, Waist Circumference.
- MESH :
- diagnosis : Metabolic Syndrome X, Obesity, Obesity, Abdominal, Overweight.
- diagnostic imaging : Intra-Abdominal Fat, Liver, Obesity, Obesity, Abdominal, Overweight.
- methods : Risk Assessment.
- Aged, Body Mass Index, Female, Humans, Male, Middle Aged, Tomography, X-Ray Computed, Waist Circumference.
Abstract
Despite its well-documented relation with visceral adiposity (VAT) and cardiometabolic risk (CMR), whether waist circumference (WC) should be measured in addition to body mass index (BMI) remains debated. This study tested the relevance of adding WC to BMI for the estimation of VAT and CMR. In the International Study of Prediction of Intra-abdominal Adiposity and Its Relationship with Cardiometabolic Risk/Intra-abdominal Adiposity, 297 physicians recruited 4,504 patients (29 countries). Both BMI and WC were measured, whereas VAT and liver fat were assessed by computed tomography. A composite CMR score was calculated. From the 4,109 patients included in the present analyses (20 ≤ BMI < 40 kg/m(2), 47% women), about 30% displayed discordant values for WC and BMI quintiles, despite a strong correlation between the 2 anthropometric variables (r = 0.87 and r = 0.84 for men and women, respectively, p <0.001). Within each single BMI unit, VAT and WC showed substantial variability between subjects (mean difference between 90th and 10th percentiles: 175 cm(2)/16 cm and 137 cm(2)/18 cm for VAT/WC in men and women, respectively). Within each BMI category, increasing gender-specific WC tertiles were associated with significantly higher VAT, liver fat, and with a more adverse CMR profile. In conclusion, this large international cardiometabolic study highlights the frequent discordance between BMI and WC, driven by the substantial variability in VAT for a given BMI. Within each BMI category, WC was cross-sectionally associated with VAT, liver fat, and CMR factors. Thus, WC allows a further refinement of the CMR related to any given BMI.
DOI: 10.1016/j.amjcard.2014.10.039
PubMed: 25499404
Affiliations:
- Allemagne, Australie, Belgique, Canada, Colombie, France, Japon, Singapour, États-Unis
- Auvergne-Rhône-Alpes, District de Dresde, Massachusetts, Rhône-Alpes, Région de Kantō, Saxe (Land), Texas, Île-de-France
- Dresde, Grenoble, Paris, Tokyo
- Université de Tokyo
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last="Borel">Anne-Laure Borel</name><affiliation wicri:level="3"><nlm:affiliation>HP2 laboratory INSERM U1042, Hôpital Universitaire de Grenoble, Pôle DIGI-DUNE, Département d'endocrinologie, Diabétologie, Maladie de la Nutrition, Grenoble, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>HP2 laboratory INSERM U1042, Hôpital Universitaire de Grenoble, Pôle DIGI-DUNE, Département d'endocrinologie, Diabétologie, Maladie de la Nutrition, Grenoble</wicri:regionArea><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Grenoble</settlement></placeName></affiliation></author><author><name sortKey="Aschner, Pablo" sort="Aschner, Pablo" uniqKey="Aschner P" first="Pablo" last="Aschner">Pablo Aschner</name><affiliation wicri:level="1"><nlm:affiliation>Javeriana University School of Medicine, Ignacio University Hospital, Bogotá, Colombia.</nlm:affiliation><country 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Hospital, Edegem, Belgium.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Department of Endocrinology, Diabetology, Metabolism and Clinical Nutrition, Antwerp University Hospital, Edegem</wicri:regionArea><wicri:noRegion>Edegem</wicri:noRegion></affiliation></author><author><name sortKey="Tan, Chee Eng" sort="Tan, Chee Eng" uniqKey="Tan C" first="Chee Eng" last="Tan">Chee Eng Tan</name><affiliation wicri:level="1"><nlm:affiliation>Gleneagles Medical Centre, Singapore.</nlm:affiliation><country xml:lang="fr">Singapour</country><wicri:regionArea>Gleneagles Medical Centre</wicri:regionArea></affiliation></author><author><name sortKey="Wittchen, Hans Ulrich" sort="Wittchen, Hans Ulrich" uniqKey="Wittchen H" first="Hans-Ulrich" last="Wittchen">Hans-Ulrich Wittchen</name><affiliation wicri:level="3"><nlm:affiliation>Institute of Clinical Psychology and Psychotherapy and Center of Clinical Epidemiology and Longitudinal Studies (CELOS), Technische Universitaet Dresden, Dresden, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Clinical Psychology and Psychotherapy and Center of Clinical Epidemiology and Longitudinal Studies (CELOS), Technische Universitaet Dresden, Dresden</wicri:regionArea><placeName><region type="land" nuts="1">Saxe (Land)</region><region type="district" nuts="2">District de Dresde</region><settlement type="city">Dresde</settlement></placeName></affiliation></author><author><name sortKey="Matsuzawa, Yuji" sort="Matsuzawa, Yuji" uniqKey="Matsuzawa Y" first="Yuji" last="Matsuzawa">Yuji Matsuzawa</name><affiliation wicri:level="1"><nlm:affiliation>Department of Endocrinology and Metabolism, Sumitomo Hospital, Osaka, Japan.</nlm:affiliation><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Endocrinology and Metabolism, Sumitomo Hospital, Osaka</wicri:regionArea><wicri:noRegion>Osaka</wicri:noRegion></affiliation></author><author><name sortKey="Kadowaki, Takashi" sort="Kadowaki, Takashi" uniqKey="Kadowaki T" first="Takashi" last="Kadowaki">Takashi Kadowaki</name><affiliation wicri:level="4"><nlm:affiliation>Department of Diabetes and Metabolic Diseases, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.</nlm:affiliation><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Diabetes and Metabolic Diseases, Graduate School of Medicine, The University of Tokyo, Tokyo</wicri:regionArea><placeName><settlement type="city">Tokyo</settlement><region type="région">Région de Kantō</region><settlement type="city">Tokyo</settlement></placeName><orgName type="university">Université de Tokyo</orgName></affiliation></author><author><name sortKey="Ross, Robert" sort="Ross, Robert" uniqKey="Ross R" first="Robert" last="Ross">Robert Ross</name><affiliation wicri:level="1"><nlm:affiliation>School of Kinesiology and Health Studies, Queen's University, Kingston, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>School of Kinesiology and Health Studies, Queen's University, Kingston, Ontario</wicri:regionArea><wicri:noRegion>Ontario</wicri:noRegion></affiliation></author><author><name sortKey="Brulle Wohlhueter, Claire" sort="Brulle Wohlhueter, Claire" uniqKey="Brulle Wohlhueter C" first="Claire" last="Brulle-Wohlhueter">Claire Brulle-Wohlhueter</name><affiliation wicri:level="3"><nlm:affiliation>Sanofi, Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Sanofi, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Almeras, Natalie" sort="Almeras, Natalie" uniqKey="Almeras N" first="Natalie" last="Alméras">Natalie Alméras</name><affiliation wicri:level="1"><nlm:affiliation>Centre de recherche de l'Institut universitaire de cardiologie et de pneumologie de Québec, Québec, Québec, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Centre de recherche de l'Institut universitaire de cardiologie et de pneumologie de Québec, Québec, Québec</wicri:regionArea><wicri:noRegion>Québec</wicri:noRegion></affiliation></author><author><name sortKey="Haffner, Steven M" sort="Haffner, Steven M" uniqKey="Haffner S" first="Steven M" last="Haffner">Steven M. Haffner</name><affiliation wicri:level="2"><nlm:affiliation>Department of Medicine, Baylor College of Medicine, Houston, Texas.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Texas</region></placeName><wicri:cityArea>Department of Medicine, Baylor College of Medicine, Houston</wicri:cityArea></affiliation></author><author><name sortKey="Balkau, Beverley" sort="Balkau, Beverley" uniqKey="Balkau B" first="Beverley" last="Balkau">Beverley Balkau</name><affiliation wicri:level="3"><nlm:affiliation>INSERM, CESP Centre for Research in Epidemiology and Population Health, UMRS 1018, Epidemiology of Diabetes, Obesity and Chronic Kidney Disease over the Lifecourse and Determinants of Early Nutrition, Villejuif, University Paris Sud 11, Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>INSERM, CESP Centre for Research in Epidemiology and Population Health, UMRS 1018, Epidemiology of Diabetes, Obesity and Chronic Kidney Disease over the Lifecourse and Determinants of Early Nutrition, Villejuif, University Paris Sud 11, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Despres, Jean Pierre" sort="Despres, Jean Pierre" uniqKey="Despres J" first="Jean-Pierre" last="Després">Jean-Pierre Després</name><affiliation wicri:level="1"><nlm:affiliation>Centre de recherche de l'Institut universitaire de cardiologie et de pneumologie de Québec, Québec, Québec, Canada. 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xml:lang="fr">France</country><wicri:regionArea>Centre de recherche de l'Institut universitaire de cardiologie et de pneumologie de Québec, Québec, Québec, Canada; CENS, CARMEN Laboratory INSERM U1060-INRA 1235, Pierre-Bénite</wicri:regionArea><wicri:noRegion>Pierre-Bénite</wicri:noRegion><wicri:noRegion>Pierre-Bénite</wicri:noRegion></affiliation></author><author><name sortKey="Smith, Jessica" sort="Smith, Jessica" uniqKey="Smith J" first="Jessica" last="Smith">Jessica Smith</name><affiliation wicri:level="2"><nlm:affiliation>Centre de recherche de l'Institut universitaire de cardiologie et de pneumologie de Québec, Québec, Québec, Canada; Harvard School of Public Health, Department of Nutrition, Boston, Massachusetts.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea>Centre de recherche de l'Institut universitaire de cardiologie et de pneumologie de Québec, Québec, Québec, Canada; Harvard School of Public Health, Department of Nutrition, Boston</wicri:cityArea></affiliation></author><author><name sortKey="Borel, Anne Laure" sort="Borel, Anne Laure" uniqKey="Borel A" first="Anne-Laure" last="Borel">Anne-Laure Borel</name><affiliation wicri:level="3"><nlm:affiliation>HP2 laboratory INSERM U1042, Hôpital Universitaire de Grenoble, Pôle DIGI-DUNE, Département d'endocrinologie, Diabétologie, Maladie de la Nutrition, Grenoble, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>HP2 laboratory INSERM U1042, Hôpital Universitaire de Grenoble, Pôle DIGI-DUNE, Département d'endocrinologie, Diabétologie, Maladie de la Nutrition, Grenoble</wicri:regionArea><placeName><region type="region">Auvergne-Rhône-Alpes</region><region type="old region">Rhône-Alpes</region><settlement type="city">Grenoble</settlement></placeName></affiliation></author><author><name sortKey="Aschner, Pablo" sort="Aschner, Pablo" uniqKey="Aschner P" first="Pablo" last="Aschner">Pablo Aschner</name><affiliation wicri:level="1"><nlm:affiliation>Javeriana University School of Medicine, Ignacio University Hospital, Bogotá, Colombia.</nlm:affiliation><country xml:lang="fr">Colombie</country><wicri:regionArea>Javeriana University School of Medicine, Ignacio University Hospital, Bogotá</wicri:regionArea><wicri:noRegion>Bogotá</wicri:noRegion></affiliation></author><author><name sortKey="Barter, Phil" sort="Barter, Phil" uniqKey="Barter P" first="Phil" last="Barter">Phil Barter</name><affiliation wicri:level="1"><nlm:affiliation>Centre for Vascular Research, Faculty of Medicine, University of New South Wales, Sydney, NSW, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Centre for Vascular Research, Faculty of Medicine, University of New South Wales, Sydney, NSW</wicri:regionArea><wicri:noRegion>NSW</wicri:noRegion></affiliation></author><author><name sortKey="Van Gaal, Luc" sort="Van Gaal, Luc" uniqKey="Van Gaal L" first="Luc" last="Van Gaal">Luc Van Gaal</name><affiliation wicri:level="1"><nlm:affiliation>Department of Endocrinology, Diabetology, Metabolism and Clinical Nutrition, Antwerp University Hospital, Edegem, Belgium.</nlm:affiliation><country xml:lang="fr">Belgique</country><wicri:regionArea>Department of Endocrinology, Diabetology, Metabolism and Clinical Nutrition, Antwerp University Hospital, Edegem</wicri:regionArea><wicri:noRegion>Edegem</wicri:noRegion></affiliation></author><author><name sortKey="Tan, Chee Eng" sort="Tan, Chee Eng" uniqKey="Tan C" first="Chee Eng" last="Tan">Chee Eng Tan</name><affiliation wicri:level="1"><nlm:affiliation>Gleneagles Medical Centre, Singapore.</nlm:affiliation><country xml:lang="fr">Singapour</country><wicri:regionArea>Gleneagles Medical Centre</wicri:regionArea></affiliation></author><author><name sortKey="Wittchen, Hans Ulrich" sort="Wittchen, Hans Ulrich" uniqKey="Wittchen H" first="Hans-Ulrich" last="Wittchen">Hans-Ulrich Wittchen</name><affiliation wicri:level="3"><nlm:affiliation>Institute of Clinical Psychology and Psychotherapy and Center of Clinical Epidemiology and Longitudinal Studies (CELOS), Technische Universitaet Dresden, Dresden, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Institute of Clinical Psychology and Psychotherapy and Center of Clinical Epidemiology and Longitudinal Studies (CELOS), Technische Universitaet Dresden, Dresden</wicri:regionArea><placeName><region type="land" nuts="1">Saxe (Land)</region><region type="district" nuts="2">District de Dresde</region><settlement type="city">Dresde</settlement></placeName></affiliation></author><author><name sortKey="Matsuzawa, Yuji" sort="Matsuzawa, Yuji" uniqKey="Matsuzawa Y" first="Yuji" last="Matsuzawa">Yuji Matsuzawa</name><affiliation wicri:level="1"><nlm:affiliation>Department of Endocrinology and Metabolism, Sumitomo Hospital, Osaka, Japan.</nlm:affiliation><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Endocrinology and Metabolism, Sumitomo Hospital, Osaka</wicri:regionArea><wicri:noRegion>Osaka</wicri:noRegion></affiliation></author><author><name sortKey="Kadowaki, Takashi" sort="Kadowaki, Takashi" uniqKey="Kadowaki T" first="Takashi" last="Kadowaki">Takashi Kadowaki</name><affiliation wicri:level="4"><nlm:affiliation>Department of Diabetes and Metabolic Diseases, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.</nlm:affiliation><country xml:lang="fr">Japon</country><wicri:regionArea>Department of Diabetes and Metabolic Diseases, Graduate School of Medicine, The University of Tokyo, Tokyo</wicri:regionArea><placeName><settlement type="city">Tokyo</settlement><region type="région">Région de Kantō</region><settlement type="city">Tokyo</settlement></placeName><orgName type="university">Université de Tokyo</orgName></affiliation></author><author><name sortKey="Ross, Robert" sort="Ross, Robert" uniqKey="Ross R" first="Robert" last="Ross">Robert Ross</name><affiliation wicri:level="1"><nlm:affiliation>School of Kinesiology and Health Studies, Queen's University, Kingston, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>School of Kinesiology and Health Studies, Queen's University, Kingston, Ontario</wicri:regionArea><wicri:noRegion>Ontario</wicri:noRegion></affiliation></author><author><name sortKey="Brulle Wohlhueter, Claire" sort="Brulle Wohlhueter, Claire" uniqKey="Brulle Wohlhueter C" first="Claire" last="Brulle-Wohlhueter">Claire Brulle-Wohlhueter</name><affiliation wicri:level="3"><nlm:affiliation>Sanofi, Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Sanofi, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Almeras, Natalie" sort="Almeras, Natalie" uniqKey="Almeras N" first="Natalie" last="Alméras">Natalie Alméras</name><affiliation wicri:level="1"><nlm:affiliation>Centre de recherche de l'Institut universitaire de cardiologie et de pneumologie de Québec, Québec, Québec, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Centre de recherche de l'Institut universitaire de cardiologie et de pneumologie de Québec, Québec, Québec</wicri:regionArea><wicri:noRegion>Québec</wicri:noRegion></affiliation></author><author><name sortKey="Haffner, Steven M" sort="Haffner, Steven M" uniqKey="Haffner S" first="Steven M" last="Haffner">Steven M. Haffner</name><affiliation wicri:level="2"><nlm:affiliation>Department of Medicine, Baylor College of Medicine, Houston, Texas.</nlm:affiliation><country xml:lang="fr">États-Unis</country><placeName><region type="state">Texas</region></placeName><wicri:cityArea>Department of Medicine, Baylor College of Medicine, Houston</wicri:cityArea></affiliation></author><author><name sortKey="Balkau, Beverley" sort="Balkau, Beverley" uniqKey="Balkau B" first="Beverley" last="Balkau">Beverley Balkau</name><affiliation wicri:level="3"><nlm:affiliation>INSERM, CESP Centre for Research in Epidemiology and Population Health, UMRS 1018, Epidemiology of Diabetes, Obesity and Chronic Kidney Disease over the Lifecourse and Determinants of Early Nutrition, Villejuif, University Paris Sud 11, Paris, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>INSERM, CESP Centre for Research in Epidemiology and Population Health, UMRS 1018, Epidemiology of Diabetes, Obesity and Chronic Kidney Disease over the Lifecourse and Determinants of Early Nutrition, Villejuif, University Paris Sud 11, Paris</wicri:regionArea><placeName><region type="region">Île-de-France</region><region type="old region">Île-de-France</region><settlement type="city">Paris</settlement></placeName></affiliation></author><author><name sortKey="Despres, Jean Pierre" sort="Despres, Jean Pierre" uniqKey="Despres J" first="Jean-Pierre" last="Després">Jean-Pierre Després</name><affiliation wicri:level="1"><nlm:affiliation>Centre de recherche de l'Institut universitaire de cardiologie et de pneumologie de Québec, Québec, Québec, Canada. Electronic address: jean-pierre.despres@criucpq.ulaval.ca.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Centre de recherche de l'Institut universitaire de cardiologie et de pneumologie de Québec, Québec, Québec</wicri:regionArea><wicri:noRegion>Québec</wicri:noRegion></affiliation></author></analytic><series><title level="j">The American journal of cardiology</title><idno type="eISSN">1879-1913</idno><imprint><date when="2015" type="published">2015</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Aged</term><term>Body Mass Index</term><term>Female</term><term>Humans</term><term>Intra-Abdominal Fat (diagnostic imaging)</term><term>Liver (diagnostic imaging)</term><term>Male</term><term>Metabolic Syndrome X (diagnosis)</term><term>Middle Aged</term><term>Obesity (diagnosis)</term><term>Obesity (diagnostic imaging)</term><term>Obesity, Abdominal (diagnosis)</term><term>Obesity, Abdominal (diagnostic imaging)</term><term>Overweight (diagnosis)</term><term>Overweight (diagnostic imaging)</term><term>Risk Assessment (methods)</term><term>Tomography, X-Ray Computed</term><term>Waist Circumference</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adulte d'âge moyen</term><term>Femelle</term><term>Foie (imagerie diagnostique)</term><term>Graisse intra-abdominale (imagerie diagnostique)</term><term>Humains</term><term>Indice de masse corporelle</term><term>Mâle</term><term>Obésité (diagnostic)</term><term>Obésité (imagerie diagnostique)</term><term>Obésité abdominale (diagnostic)</term><term>Obésité abdominale (imagerie diagnostique)</term><term>Sujet âgé</term><term>Surpoids (diagnostic)</term><term>Surpoids (imagerie diagnostique)</term><term>Syndrome métabolique X (diagnostic)</term><term>Tomodensitométrie</term><term>Tour de taille</term><term>Évaluation des risques ()</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Metabolic Syndrome X</term><term>Obesity</term><term>Obesity, Abdominal</term><term>Overweight</term></keywords><keywords scheme="MESH" qualifier="diagnostic" xml:lang="fr"><term>Obésité</term><term>Obésité abdominale</term><term>Surpoids</term><term>Syndrome métabolique X</term></keywords><keywords scheme="MESH" qualifier="diagnostic imaging" xml:lang="en"><term>Intra-Abdominal Fat</term><term>Liver</term><term>Obesity</term><term>Obesity, Abdominal</term><term>Overweight</term></keywords><keywords scheme="MESH" qualifier="imagerie diagnostique" xml:lang="fr"><term>Foie</term><term>Graisse intra-abdominale</term><term>Obésité</term><term>Obésité abdominale</term><term>Surpoids</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Risk Assessment</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Aged</term><term>Body Mass Index</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Tomography, X-Ray Computed</term><term>Waist Circumference</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adulte d'âge moyen</term><term>Femelle</term><term>Humains</term><term>Indice de masse corporelle</term><term>Mâle</term><term>Sujet âgé</term><term>Tomodensitométrie</term><term>Tour de taille</term><term>Évaluation des risques</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Despite its well-documented relation with visceral adiposity (VAT) and cardiometabolic risk (CMR), whether waist circumference (WC) should be measured in addition to body mass index (BMI) remains debated. This study tested the relevance of adding WC to BMI for the estimation of VAT and CMR. In the International Study of Prediction of Intra-abdominal Adiposity and Its Relationship with Cardiometabolic Risk/Intra-abdominal Adiposity, 297 physicians recruited 4,504 patients (29 countries). Both BMI and WC were measured, whereas VAT and liver fat were assessed by computed tomography. A composite CMR score was calculated. From the 4,109 patients included in the present analyses (20 ≤ BMI < 40 kg/m(2), 47% women), about 30% displayed discordant values for WC and BMI quintiles, despite a strong correlation between the 2 anthropometric variables (r = 0.87 and r = 0.84 for men and women, respectively, p <0.001). Within each single BMI unit, VAT and WC showed substantial variability between subjects (mean difference between 90th and 10th percentiles: 175 cm(2)/16 cm and 137 cm(2)/18 cm for VAT/WC in men and women, respectively). Within each BMI category, increasing gender-specific WC tertiles were associated with significantly higher VAT, liver fat, and with a more adverse CMR profile. In conclusion, this large international cardiometabolic study highlights the frequent discordance between BMI and WC, driven by the substantial variability in VAT for a given BMI. Within each BMI category, WC was cross-sectionally associated with VAT, liver fat, and CMR factors. Thus, WC allows a further refinement of the CMR related to any given BMI.</div></front></TEI><affiliations><list><country><li>Allemagne</li><li>Australie</li><li>Belgique</li><li>Canada</li><li>Colombie</li><li>France</li><li>Japon</li><li>Singapour</li><li>États-Unis</li></country><region><li>Auvergne-Rhône-Alpes</li><li>District de Dresde</li><li>Massachusetts</li><li>Rhône-Alpes</li><li>Région de Kantō</li><li>Saxe (Land)</li><li>Texas</li><li>Île-de-France</li></region><settlement><li>Dresde</li><li>Grenoble</li><li>Paris</li><li>Tokyo</li></settlement><orgName><li>Université de Tokyo</li></orgName></list><tree><country name="France"><noRegion><name sortKey="Nazare, Julie Anne" sort="Nazare, Julie Anne" uniqKey="Nazare J" first="Julie-Anne" last="Nazare">Julie-Anne Nazare</name></noRegion><name sortKey="Balkau, Beverley" sort="Balkau, Beverley" uniqKey="Balkau B" first="Beverley" last="Balkau">Beverley Balkau</name><name sortKey="Borel, Anne Laure" sort="Borel, Anne Laure" uniqKey="Borel A" first="Anne-Laure" last="Borel">Anne-Laure Borel</name><name sortKey="Brulle Wohlhueter, Claire" sort="Brulle Wohlhueter, Claire" uniqKey="Brulle Wohlhueter C" first="Claire" last="Brulle-Wohlhueter">Claire Brulle-Wohlhueter</name></country><country name="États-Unis"><region name="Massachusetts"><name sortKey="Smith, Jessica" sort="Smith, Jessica" uniqKey="Smith J" first="Jessica" last="Smith">Jessica Smith</name></region><name sortKey="Haffner, Steven M" sort="Haffner, Steven M" uniqKey="Haffner S" first="Steven M" last="Haffner">Steven M. Haffner</name></country><country name="Colombie"><noRegion><name sortKey="Aschner, Pablo" sort="Aschner, Pablo" uniqKey="Aschner P" first="Pablo" last="Aschner">Pablo Aschner</name></noRegion></country><country name="Australie"><noRegion><name sortKey="Barter, Phil" sort="Barter, Phil" uniqKey="Barter P" first="Phil" last="Barter">Phil Barter</name></noRegion></country><country name="Belgique"><noRegion><name sortKey="Van Gaal, Luc" sort="Van Gaal, Luc" uniqKey="Van Gaal L" first="Luc" last="Van Gaal">Luc Van Gaal</name></noRegion></country><country name="Singapour"><noRegion><name sortKey="Tan, Chee Eng" sort="Tan, Chee Eng" uniqKey="Tan C" first="Chee Eng" last="Tan">Chee Eng Tan</name></noRegion></country><country name="Allemagne"><region name="Saxe (Land)"><name sortKey="Wittchen, Hans Ulrich" sort="Wittchen, Hans Ulrich" uniqKey="Wittchen H" first="Hans-Ulrich" last="Wittchen">Hans-Ulrich Wittchen</name></region></country><country name="Japon"><noRegion><name sortKey="Matsuzawa, Yuji" sort="Matsuzawa, Yuji" uniqKey="Matsuzawa Y" first="Yuji" last="Matsuzawa">Yuji Matsuzawa</name></noRegion><name sortKey="Kadowaki, Takashi" sort="Kadowaki, Takashi" uniqKey="Kadowaki T" first="Takashi" last="Kadowaki">Takashi Kadowaki</name></country><country name="Canada"><noRegion><name sortKey="Ross, Robert" sort="Ross, Robert" uniqKey="Ross R" first="Robert" last="Ross">Robert Ross</name></noRegion><name sortKey="Almeras, Natalie" sort="Almeras, Natalie" uniqKey="Almeras N" first="Natalie" last="Alméras">Natalie Alméras</name><name sortKey="Despres, Jean Pierre" sort="Despres, Jean Pierre" uniqKey="Despres J" first="Jean-Pierre" last="Després">Jean-Pierre Després</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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